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LY-294002 hydrochloride

CAS No. 934389-88-5

LY-294002 hydrochloride ( —— )

Catalog No. M19270 CAS No. 934389-88-5

LY294002 is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation.

Purity : 97%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    LY-294002 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    LY294002 is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation.
  • Description
    LY294002 is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    p110α; p110β; p110δ
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    934389-88-5
  • Formula Weight
    343.81
  • Molecular Formula
    C19H17NO3·HCl
  • Purity
    97%
  • Solubility
    ——
  • SMILES
    C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chaussade C, et al. Evidence for functional redundancy of class IA PI3K isoforms in insulin signalling. Biochem J. 2007 Jun 15;404(3):449-58.
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